SCIENTIFIC PUBLICATIONS

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  • Long-term edaravone efficacy in amyotrophic lateral sclerosis: post-hoc analyses of Study 19 (MCI186-19)
    —Shefner J, Heiman‐Patterson T, Pioro EP, et al. Long‐term edaravone efficacy in amyotrophic lateral sclerosis: Post‐hoc analyses of Study 19 (MCI186‐19). Muscle & Nerve. 2019;61(2):218-221. doi:10.1002/mus.26740.
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  • Post-hoc analysis of the edaravone clinical trials Study 16 and Study 19: a step toward more efficient clinical trial designs in amyotrophic lateral sclerosis
    —Palumbo JM, Hubble J, Apple S, et al. Post-hoc analyses of the edaravone clinical trials Study 16 and Study 19: a step toward more efficient clinical trial designs in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 2019;20(5-6):421-431. doi:10.1080/21678421.2019.1599955.
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  • A post-hoc subgroup analysis of outcomes in the first phase III clinical study of edaravone (MCI-186) in amyotrophic lateral sclerosis
    —The Edaravone (MCI-186) ALS 16 Study Group. A post-hoc subgroup analysis of outcomes in the first phase III clinical study of edaravone (MCI-186) in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 2017;18(sup1):11-19. doi:10.1080/21678421.2017.1363780.
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  • Safety and efficacy of edaravone in well defined patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial
    —The Writing Group on behalf of the Edaravone (MCI-186) ALS 19 Study Group. Safety and efficacy of edaravone in well defined patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial. The Lancet Neurology. 2017;16(7):505-512. doi: 1016/S1474-4422(17)30115-1.
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  • Mitsubishi Tanabe Pharma America presented real-world data on edaravone for ALS at the 30th International Symposium on ALS/MND
    —Heiman-Patterson, T, Perdrizet, J, Apple, S, et al. Real-World Evidence of Edaravone for Amyotrophic Lateral Sclerosis from a National Infusion Center Database in the United States. Poster presented at: 30th International Symposium on ALS/MND; December 5, 2019; Perth, Australia.
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The studies referenced herein are provided for general information only and are not intended as statements about the safety or efficacy of any product.